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A native of Compton, California, Wiley played college football at Columbia University, helping the Ivy League program improve from a 2-8 record his freshman year to 8-2 his senior season. He earned 1st team All-Conference honors in 1994, and was named Sports Illustrated National Defensive Player of the Week when he had two sacks, a forced and recovered a fumble, intercepted a pass and scored a touchdown as a running back while playing on both sides of the ball against Yale. He also earned All-American and All-Conference honors in 1996 and was named the Sid Luckman team MVP.  

A second-round pick of the Buffalo Bills in the 1997 NFL Draft, Wiley played for four teams throughout his career which included:  Buffalo (1997-2000), San Diego Chargers (2001-03), Dallas Cowboys (2004) and Jacksonville Jaguars (2005-06). Wiley was considered one of the NFL’s top defensive players during the prime of his career.Wiley graduated from Columbia University in 1997 with a Bachelor of Science degree in Sociology. He was inducted into the Columbia University Athletics Hall of Fame in its inaugural class in 2006, but more impressively he was inducted into the Ivy League Hall of Fame in 2012.

In 2001, Wiley led the Chargers with a career-high of 13 sacks and five forced fumbles. He was voted as a starter for the AFC in the Pro Bowl, and also named into Pro Football Weekly’s All-AFC Team. During his previous season with the Bills, Wiley had an outstanding year as well leading the team with 10.5 sacks.

During his NFL career, Wiley had the honor of being named one of the Top 50 Players in the NFL, twice, by Pro Football Weekly. He was also nominated for the Walter Payton Man of the Year three times for his volunteering and charity work.

Wiley first made his transition from the NFL to ESPN in 2007, where he started off as a studio analyst on ESPN2’s First Take. Shortly after, in 2008, he became a game day analyst for ESPN’s Arena Football League telecasts. With such a charismatic personality, it was no surprise when Wiley was named co-host of Winners Bracket with Michelle Beadle in 2010. 

Wiley continued to expand his ESPN role when he was named co-host of "Afternoons On ESPNLA With Marcellus & Kelvin” on 710AM ESPN Radio Los Angeles. With the talented Kelvin Washington, the program airs weekdays 3 p.m. – 7 p.m. (PST), and features stimulating discussions on the latest sports news and events.

Wiley took on his full-time co-host position on SportsNation, which airs weekdays 1 p.m. (PST),  in January of 2013.  Alongside Michelle Beadle, SportsNation’s is a lighthearted and opinionated sports show powered by the people of the sporting nation, you!

Wiley enjoys spending time with his wife, Annemarie, and his two children, Morocca and Marcellus Junior.  He’s also an accomplished DJ under the moniker "Dat Dude” and a philanthropist with a strong passion for helping underserved children receiving assistance with educational and sports needs.